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胆囊的核心功能是浓缩、储存胆汁。肝脏24小时持续分泌稀薄胆汁，胆囊会将胆汁浓缩5至10倍储存，进食油腻肉食时一次性释放大量胆汁，高效分解脂肪。胆囊切除后，储存胆汁的“仓库”消失，肝脏分泌的胆汁只能持续少量流入肠道，短时间内无法分解大量脂肪，一次性摄入过多肥肉、重油肉食，容易引发腹胀、腹泻、反酸，医学上称为胆囊切除术后腹泻，约30%患者术后短期会出现该症状。但该不适大多属于阶段性反应，术后3至6个月，胆管会代偿性扩张，替代部分胆囊储存功能，脂肪消化能力会逐步提升。

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